New Regulator For Blood Cancer Development Identified
KL-key research area oncology: A research team led by physicians of the Karl Landsteiner University of Health Sciences in Krems (KL Krems) uncovers a pivotal role for a regulator protein in tumour bone marrow angiogenesis.
Krems, 23th June 2021 – A specific regulatory protein significantly influences the development of tumour-inducing blood vessels in the bone marrow of blood cancer patients. Using a series of different experiments, the team identified that a transcription factor known as JunB is central for the formation of new blood vessels in the bone marrow of patients suffering from multiple myeloma (MM). The findings, which have been published in the journal Leukemia, could pave the way for novel treatment approaches for this still incurable disease.
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