Prospective analysis of radiation-induced contrast enhancement (RICE)
... and health-related quality of life following proton therapy for CNS and skull base tumors
Recent publication
This prospective study investigated the incidence, characteristics and risk factors of radiation-induced contrast enhancement in the brain after proton radiotherapy. Contrast enhancement was detected in 15% of 421 patients between 2017 and 2021, with an average follow-up of 24 months. Risk factors were identified and the impact on quality of life was assessed using a questionnaire. The international collaboration included researchers from the Division of Biostatistics and Data Science at Karl Landsteiner University and the Division of Radiotherapy - Radiation Oncology at Krems University Hospital. The study was led by scientists at MedAustron, which is a teaching and research site of the Karl Landsteiner University. The work has been published in the International Journal of Radiation Oncology*Biology*Physics.
Lütgendorf-Caucig C, Pelak M, Hug E, Flechl B, Surböck B, Marosi C et al. Prospective analysis of radiation-induced contrast enhancement (RICE) and health-related quality of life following proton therapy for CNS and skull base tumors. International Journal of Radiation Oncology Biology Physics. 2024 Jan 18. Epub 2024 Jan 18. doi: 10.1016/j.ijrobp.2024.01.007
Univ.-Prof. Dr. Piero Fossati MD
Head of
Division of Radiation Oncology with an emphasis on Particle Therapy
Univ.-Prof. PD DI Markus Stock PhD
Head of
Division of Medical Physics with an emphasis on Particle Therapy
Dr. Uwe Graichen
Scientific Staff (PostDoc)
Division of Biostatistics and Data Science
Univ.-Prof. Dr. Sascha Klee
Head of, Member of the Senate, Member of the Committee for Scientific Integrity and Ethics
Division of Biostatistics and Data Science
Prim. Clin. Ass. Prof. Dr. Petra Georg MBA
Division of Radiotherapy - Radiation Oncology (University Hospital Krems)
