• Research blog
Wednesday, 10. January 2024

Epidemiological cut-off values for non-O1/ non-O139 Vibrio cholerae disc diffusion data

... generated by standardised methods


Recent publication


Two specific serogroups (O1 and O139) of the bacterium Vibrio cholerae cause cholera. Non-cholera-causing serogroups (non-O1 and non-O139) of Vibrio cholerae are found in the environment, particularly in aquatic systems. A guideline from the Global Laboratory Standards Institute (GLSI), a sub-organisation of the International Organisation for Standardisation (ISO), also specifies limits for test systems to detect these non-cholera-causing Vibrio cholerae bacteria. According to an international research group, the previous definition of these limits for non-O1 and non-O139 Vibrio cholerae tested with different antimicrobial agents made some inappropriate assumptions. Therefore, this research group has developed new limits on standardised test systems specifically for susceptibility testing of non-O1 and non-O139 Vibrio cholerae bacteria in the environment. These will be submitted to GLSI and incorporated into future guidelines for laboratory diagnostics and in vitro testing. The ICC Water & Health was involved in the study, as were researchers from the Divison of Water Quality and Health at KL. The protocol and results can be read free of charge in the scientific journal "Diseases of Aquatic Organisms".

Smith P, Le Devendec L, Jouy E, Larvor E, Lesne J, Kirschner AKT et al. Epidemiological cut-off values for non-O1/ non-O139 Vibrio cholerae disc diffusion data generated by standardised methods. Diseases of Aquatic Organisms. 2023 Dec 14;156:115-121. doi: 10.3354/dao03766

Assoc. Prof. PD Mag. Dr. Alexander Kirschner

Assoc. Prof. PD Mag. Dr. Alexander Kirschner

Scientific Staff (Sen. PostDoc)
Division of Water Quality and Health

Melanie Leopold MSc

Melanie Leopold MSc

Scientific Staff (PreDoc)
Division of Water Quality and Health