Acute myeloid leukemia patient with active disseminated tuberculosis
... bridged to transplant with reduced 14-day venetoclax and azacitidine schedule
Recent publication
Dr Theresa Lentner, BSc and Dr Gerhard Krajnik, both physicians at the Division of Internal Medicine 1 at St. Pölten University Hospital, published the case of a patient suffering from acute myeloid leukaemia and tuberculosis with intestinal perforation in the journal MEMO (Magazine of European Medical Oncology). Her poor state of health and the risk of drug interactions make high-dose therapy, which would be indicated, impossible. The treating physicians decide on a shortened and simultaneous antileukaemic and antitubercular therapy regimen, which leads to remission in the patient without any undesirable side effects. The case is freely accessible thanks to open access funding from Karl Landsteiner University and shows how patients who are eligible for a transplant can be well treated with the drugs venetoclax and azacitidine until then.
Lentner T, Krajnik G. Acute myeloid leukemia patient with active disseminated tuberculosis bridged to transplant with reduced 14-day venetoclax and azacitidine schedule. Memo - Magazine of European Medical Oncology. 2024 Jan. Epub 2024 Jan. doi: 10.1007/s12254-023-00947-5
Dr. Theresa Lentner BSc
Division of Internal Medicine 1 (University Hospital St. Pölten)
Dr. Gerhard Krajnik
Division of Internal Medicine 1 (University Hospital St. Pölten)
