• Research blog
Monday, 12. February 2024

New insights into neuropathology and pathogenesis of autoimmune glial fibrillary acidic protein meningoencephalomyelitis

Recent publication


Autoimmune GFAP astrocytopathy is a rare form of non-infectious meningoencephalitis. The results of 2 autopsies and 9 biopsies in the central nervous system of patients provide new pathophysiological insights into the disease. St. Pölten University Hospital also provided data for the study, which was funded by the Austrian Science Fund and the Austrian Society of Neurology. Results are freely available in the journal Acta Neuropathologica.

Guo, Y, Endmayr, V, Zekeridou, A, McKeon, A, Leypoldt, F, Hess, K, Kalinowska-Lyszczarz, A, Klang, A, Pakozdy, A, Höftberger, E, Hametner, S, Haider, C, De Simoni, D, Peters, S, Gelpi, E, Röcken, C, Oberndorfer, S, Lassmann, H, Lucchinetti, CF & Höftberger, R 2024, 'New insights into neuropathology and pathogenesis of autoimmune glial fibrillary acidic protein meningoencephalomyelitis', Acta Neuropathologica, vol. 147, no. 1, pp. 31. https://doi.org/10.1007/s00401-023-02678-7

Prim. Assoc. Prof. PD Dr. Stefan Oberndorfer FEAN

Division of Neurology (University Hospital St. Pölten)