• Research blog
Wednesday, 13. March 2024

The impact of concomitant chronic total occlusion on clinical outcomes

... in patients undergoing transcatheter aortic valve replacement: a large single-center analysis


Recent publication


Researchers from the Division of Internal Medicine 3 at the KL University Hospital at St. Pölten investigated the incidence of chronic total occlusions in patients with coronary artery disease who underwent transcatheter aortic valve replacement surgery. A total of 1487 cases were retrospectively analysed. 11.2 percent had chronic total occlusion before surgery. Doctors analysed the effect of these total occlusions on patient mortality. The data suggest that further analysis in a subgroup is warranted to investigate the significance of existing chronic total occlusion as a predictive parameter. Thanks to open access funding from KL, the paper has been published freely available in “Frontiers in Cardiovascular Medicine”. Dr Maximilian Will is the first and the corresponding author for the study. He is conducting his research as part of a Research Time Out (RTO), a funding instrument of the "Forschungsimpulse" package of measures to promote clinical research at university hospitals of the Karl Landsteiner University of Health Sciences.

Will, M, Schwarz, K, Weiss, T, Leibundgut, G, Schmidt, E, Vock, P, Mousavi, R, Borovac, JA, Kwok, CS, Hoppe, UC, Mascherbauer, J & Lamm, G 2024, 'The impact of concomitant chronic total occlusion on clinical outcomes in patients undergoing transcatheter aortic valve replacement: a large single-center analysis', Frontiers in Cardiovascular Medicine, vol. 11. https://doi.org/10.3389/fcvm.2024.1338253

Prim. Univ.-Prof. Dr. Julia Mascherbauer

Division of Internal Medicine 3 (University Hospital St. Pölten)