Rudolf Valenta, M.D.

danube.arc@kl.ac.at

Publikationen

2022
- Zeitschriftenartikel
  - Diós, Á., Srinivasan, B., Gyimesi, J., Werkstetter, K., Valenta, R., Koletzko, S. & Korponay-Szabó, I.R., 2022. Changes in Non-Deamidated versus Deamidated Epitope Targeting and Disease Prediction during the Antibody Response to Gliadin and Transglutaminase of Infants at Risk for Celiac Disease. International journal of molecular sciences, 23(5), S.2498 [pii].
  - Farag, A.K., Roesner, L.M., Wieschowski, S., Heratizadeh, A., Eiz-Vesper, B., Kwok, W.W., Valenta, R. & Werfel, T., 2022. Specific T cells targeting Staphylococcus aureus fibronectin-binding protein 1 induce a type 2/type 1 inflammatory response in sensitized atopic dermatitis patients. Allergy, 77(4), S.1245-1253.
  - Gattinger, P., Huang, H.-J., Valenta, R. & Vrtala, S., 2022. Response to González-Pérez et al. The Journal of investigative dermatology, 142(3 Pt A), S.723-726.
    Link
  - Gattinger, P., Kratzer, B., Tulaeva, I., Niespodziana, K., Ohradanova-Repic, A., Gebetsberger, L., Borochova, K., Garner-Spitzer, E., Trapin, D., Hofer, G., Keller, W., Baumgartner, I., Tancevski, I., Khaitov, M., Karaulov, A., Stockinger, H., Wiedermann, U., Pickl, W.F. & Valenta, R., 2022. Vaccine based on folded RBD-PreS fusion protein with potential to induce sterilizing immunity to SARS-CoV-2 variants. Allergy.
  - Gattinger, P., Tulaeva, I., Borochova, K., Kratzer, B., Trapin, D., Kropfmüller, A., Pickl, W.F. & Valenta, R., 2022. Omicron: A SARS-CoV-2 variant of real concern. Allergy.
  - Kopanja, S., Gattinger, P., Schmidthaler, K., Sieber, J., Niepodziana, K., Schlederer, T., Weseslindtner, L., Stiasny, K., Götzinger, F., Pickl, W.F., Frischer, T., Valenta, R. & Szepfalusi, Z., 2022. Characterization of the antibody response to SARS-CoV-2 in a mildly affected pediatric population. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 33(2), S.e13737.
  - Kratzer, B., Schlax, L.C., Gattinger, P., Waidhofer-Söllner, P., Trapin, D., Tauber, P.A., Sehgal, A.Nasar Ahme, Kormoczi, U., Rottal, A., Feichter, M., Oberhofer, T., Grabmeier-Pfistershammer, K., Borochova, K., Dorofeeva, Y., Tulaeva, I., Weber, M., Mühl, B., Kropfmüller, A., Negrin, B., Kundi, M., Valenta, R. & Pickl, W.F., 2022. Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response. Allergy.
  - Niespodziana, K., Cabauatan, C.R., Pazderova, P., Vacal, P.C., Wortmann, J., Keller, W., Errhalt, P. & Valenta, R., 2022. Identification of Epitopes on Rhinovirus 89 Capsid Proteins Capable of Inducing Neutralizing Antibodies. International journal of molecular sciences, 23(9), S.5113.
  - Potapova, E., Le Floch, V.Bordas-, Schlederer, T., Vrtala, S., Huang, H.-J., Canonica, G.W., Valenta, R., Matricardi, P.M. & Mascarell, L., 2022. Molecular reactivity profiling upon immunotherapy with a 300 IR sublingual house dust mite tablet reveals marked humoral changes towards major allergens. Allergy.
    Link
  - Zabel, M., Weber, M., Kratzer, B., Köhler, C., Jahn-Schmid, B., Gadermaier, G., Gattinger, P., Bidovec-Stojkovic, U., Korosec, P., Smole, U., Wurzinger, G., Chen, K.-W., Panaitescu, C.Bunu, Klimek, L., Pablos, I., Niespodziana, K., Neunkirchner, A., Keller, W., Valenta, R. & Pickl, W.F., 2022. Art v 1 IgE epitopes of patients and humanized mice are conformational. The Journal of allergy and clinical immunology, S.S0091-6749(22)00701-1.
2021
- Zeitschriftenartikel
  - Agerer, B., Koblischke, M., Gudipati, V., Montano-Gutierrez, L.Fernando, Smyth, M., Popa, A., Genger, J.-W., Endler, L., Florian, D.M., Mühlgrabner, V., Graninger, M., Aberle, S.W., Husa, A.-M., Shaw, L.Ellen, Lercher, A., Gattinger, P., Torralba-Gombau, R., Trapin, D., Penz, T., Barreca, D., Fae, I., Wenda, S., Traugott, M., Walder, G., Pickl, W.F., Thiel, V., Allerberger, F., Stockinger, H., Puchhammer-Stöckl, E., Weninger, W., Fischer, G., Hoepler, W., Pawelka, E., Zoufaly, A., Valenta, R., Bock, C., Paster, W., Geyeregger, R., Farlik, M., Halbritter, F., Huppa, J.B., Aberle, J.H. & Bergthaler, A., 2021. SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8(+) T cell responses. Science immunology, 6(57).
  - Akarsu, A., Soyer, O., Sahiner, U.Murat, Valenta, R. & Sekerel, B.Enis, 2021. Improving the diagnostic utility of lip dose challenges to diagnose tree nut allergy. The journal of allergy and clinical immunology. In practice, 9(1), S.534-536.e2.
    Link
  - Akinfenwa, O., Huang, H.J., Linhart, B., Focke-Tejkl, M., Vrtala, S., Poroshina, A., Nikonova, A., Khaitov, M., Campion, N.J., Eckl-Dorna, J., Niederberger-Leppin, V., Kratzer, B., Tauber, P.A., Pickl, W.F., Kundi, M., Campana, R. & Valenta, R., 2021. Preventive Administration of Non-Allergenic Bet v 1 Peptides Reduces Allergic Sensitization to Major Birch Pollen Allergen, Bet v 1. Frontiers in Immunology, 12, S.744544.
  - Akinfenwa, O., Rodriguez-Dominguez, A., Vrtala, S., Valenta, R. & Campana, R., 2021. Novel vaccines for allergen-specific immunotherapy. Current opinion in allergy and clinical immunology, 21(1), S.86-99.
  - Borochova, K., Niespodziana, K., Focke-Tejkl, M., Hofer, G., Keller, W. & Valenta, R., 2021. Dissociation of the respiratory syncytial virus F protein-specific human IgG, IgA and IgM response. Scientific reports, 11(1), S.3551.
  - Caraballo, L., Valenta, R., Acevedo, N. & Zakzuk, J., 2021. Are the Terms Major and Minor Allergens Useful for Precision Allergology?. Frontiers in immunology, 12, S.651500.
  - Curin, M., Huang, H.-J., Garmatiuk, T., Gutfreund, S., Resch-Marat, Y., Chen, K.-W., Fauland, K., Keller, W., Zieglmayer, P., Zieglmayer, R., Lemell, P., Horak, F., Hemmer, W., Focke-Tejkl, M., Flicker, S., Vrtala, S. & Valenta, R., 2021. IgE Epitopes of the House Dust Mite Allergen Der p 7 Are Mainly Discontinuous and Conformational. Frontiers in immunology, 12, S.687294.
  - D'Souza, N., Weber, M., Sarzsinszky, E., Vrtala, S., Curin, M., Schaar, M., Garib, V., Focke-Tejkl, M., Li, Y., Jones, R., Chen, H., Valenta, R. & Sun, B., 2021. The Molecular Allergen Recognition Profile in China as Basis for Allergen-Specific Immunotherapy. Frontiers in immunology, 12, S.719573.
  - Fuhrmann, V., Huang, H.J., Akarsu, A., Shilovskiy, I., Elisyutina, O., Khaitov, M., van Hage, M., Linhart, B., Focke-Tejkl, M., Valenta, R. & Sekerel, B.E., 2021. From Allergen Molecules to Molecular Immunotherapy of Nut Allergy: A Hard Nut to Crack. Frontiers in Immunology, 12, S.742732.
  - Garib, V., Ben-Ali, M., Kundi, M., Curin, M., Yaakoubi, R., Ben-Mustapha, I., Mekki, N., Froeschl, R., Perkmann, T., Valenta, R. & Barbouche, M.-R., 2021. Profound differences in IgE and IgG recognition of micro-arrayed allergens in hyper IgE syndromes. Allergy.
  - Gattinger, P., Niespodziana, K., Stiasny, K., Sahanic, S., Tulaeva, I., Borochova, K., Dorofeeva, Y., Schlederer, T., Sonnweber, T., Hofer, G., Kiss, R., Kratzer, B., Trapin, D., Tauber, P.A., Rottal, A., Kormoczi, U., Feichter, M., Weber, M., Focke-Tejkl, M., Löffler-Ragg, J., Mühl, B., Kropfmüller, A., Keller, W., Stolz, F., Henning, R., Tancevski, I., Puchhammer-Stöckl, E., Pickl, W.F. & Valenta, R., 2021. Neutralization of SARS-CoV-2 requires antibodies against conformational receptor-binding domain epitopes. Allergy.
  - Gheerbrant, H., Guillien, A., Vernet, R., Lupinek, C., Pison, C., Pin, I., Demenais, F., Nadif, R., Bousquet, J., Pickl, W.F., Valenta, R., Bouzigon, E. & Siroux, V., 2021. Associations between specific IgE sensitization to 26 respiratory allergen molecules and HLA class II alleles in the EGEA cohort. Allergy.
    Link
  - Huang, H.-J., Campana, R., Akinfenwa, O., Curin, M., Sarzsinszky, E., Karsonova, A., Riabova, K., Karaulov, A., Niespodziana, K., Elisyutina, O., Fedenko, E., Litovkina, A., Smolnikov, E., Khaitov, M., Vrtala, S., Schlederer, T. & Valenta, R., 2021. Microarray-Based Allergy Diagnosis: Quo Vadis?. Frontiers in Immunology, 11.
  - Huang, H.-J., Resch-Marat, Y., Casset, A., Weghofer, M., Zieglmayer, P., Ing, R.Zieglmayer, Lemell, P., Horak, F., Chen, K.-W., Potapova, E., Matricardi, P.M., Pauli, G., Grote, M., Valenta, R. & Vrtala, S., 2021. IgE-recognition of the house dust mite allergen Der p 37 is associated with asthma. The Journal of allergy and clinical immunology, S.S0091-6749(21)01294-X [pii].
  - Karsonova, A.V., Riabova, K.A., Khaitov, M.R., Elisyutina, O.G., Ilina, N., Fedenko, E.S., Fomina, D.S., Beltyukov, E., Bondarenko, N.L., Evsegneeva, I.V., Glazkova, P.A., Semenov, D.Yu, van Hage, M., Gronlund, H., Karaulov, A.V., Valenta, R. & Curin, M., 2021. Milk-Specific IgE Reactivity Without Symptoms in Albumin-Sensitized Cat Allergic Patients. Allergy, asthma & immunology research, 13(4), S.668-670.
  - Melén, E., Standl, M., Gehring, U., Altug, H., Antó, J.Maria, Berdel, D., Bergström, A., Bousquet, J., Heinrich, J., Koppelman, G.H., Kull, I., Lupinek, C., Markevych, I., Schikowski, T., Thiering, E., Valenta, R., van Hage, M., von Berg, A., Vonk, J.M., Wickman, M., Wijga, A. & Gruzieva, O., 2021. Air pollution and IgE sensitization in 4 European birth cohorts-the MeDALL project. The Journal of allergy and clinical immunology, 147(2), S.713-722.
  - Muddaluru, V., Valenta, R., Vrtala, S., Schlederer, T., Hindley, J., Hickey, P., Larché, M. & Tonti, E., 2021. Comparison of house dust mite sensitization profiles in allergic adults from Canada, Europe, South Africa and USA. Allergy, 76(7), S.2177-2188.
    Link
  - Niespodziana, K., Stenberg-Hammar, K., Papadopoulos, N.G., Focke-Tejkl, M., Errhalt, P., Konradsen, J.R., Söderhall, C., van Hage, M., Hedlin, G. & Valenta, R., 2021. Microarray Technology May Reveal the Contribution of Allergen Exposure and Rhinovirus Infections as Possible Triggers for Acute Wheezing Attacks in Preschool Children. Viruses, 13(5), S.915.
  - Palmrich, P., Roessler, B., Wisgrill, L., Kampf, S., Gattinger, P., Valenta, R., Fleischmann, E., Berger, A., Kiss, H. & Farr, A., 2021. Multiprofessional perinatal care in a pregnant patient with acute respiratory distress syndrome due to COVID-19. BMC pregnancy and childbirth, 21(1), S.587.
  - Sarzsinszky, E., Lupinek, C., Vrtala, S., Huang, H.Jy, Hofer, G., Keller, W., Chen, K.Wei, Panaitescu, C.Bunu, Resch-Marat, Y., Zieglmayer, R., Lemell, P., Zieglmayer, P., Horak, F., Duchene, M. & Valenta, R., 2021. Expression in Escherichia coli and Purification of Folded rDer p 20, the Arginine Kinase From Dermatophagoides pteronyssinus: A Possible Biomarker for Allergic Asthma. Allergy, asthma & immunology research, 13(1), S.154-163.
  - Shamji, M.H., Valenta, R., Jardetzky, T., Verhasselt, V., Durham, S.R., Wurtzen, P.A. & van Neerven, R.J.J., 2021. Invited review: The role of allergen-specific IgE, IgG and IgA in allergic disease. Allergy.
  - Siroux, V., Boudier, A., Bousquet, J., Dumas, O., Just, J., Le Moual, N., Nadif, R., Varraso, R., Valenta, R. & Pin, I., 2021. Trajectories of IgE sensitization to allergen molecules from childhood to adulthood and respiratory health in the EGEA cohort. Allergy.
    Link
  - Xepapadaki, P., Christopoulou, G., Stavroulakis, G., Freidl, R., Linhart, B., Zuidmeer, L., Lakoumentas, J., van Ree, R., Valenta, R. & Papadopoulos, N.G., 2021. Natural history of IgE-mediated fish allergy in children. The Journal of Allergy and Clinical Immunology: In Practice.
    Link
  - Zghaebi, M., Byazrova, M., Flicker, S., Villazala-Merino, S., Campion, N.J., Stanek, V., Tu, A., Breiteneder, H., Filatov, A., Khaitov, M., Niederberger-Leppin, V., Eckl-Dorna, J. & Valenta, R., 2021. Tracing Human IgE B Cell Antigen Receptor-Bearing Cells With a Monoclonal Anti-Human IgE Antibody That Specifically Recognizes Non-Receptor-Bound IgE. Frontiers in Immunology, 12, S.803236.
2020
- Zeitschriftenartikel
  - Borochova, K., Niespodziana, K., Hammar, K.Stenberg, van Hage, M., Hedlin, G., Söderhall, C., Focke-Tejkl, M. & Valenta, R., 2020. Features of the Human Antibody Response against the Respiratory Syncytial Virus Surface Glycoprotein G. Vaccines, 8(2).
  - Elisyutina, O., Lupinek, C., Fedenko, E., Litovkina, A., Smolnikov, E., Ilina, N., Kudlay, D., Shilovskiy, I., Valenta, R. & Khaitov, M., 2020. IgE-reactivity profiles to allergen molecules in Russian children with and without symptoms of allergy revealed by micro-array analysis. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
    Link
  - Gattinger, P., Bidovec-Stojkovic, U., Zidarn, M., Korosec, P., Valenta, R. & Mittermann, I., 2020. Glycosylation enhances allergenic activity of major bee venom allergen Api m 1 by adding IgE epitopes. The Journal of allergy and clinical immunology.
  - Gattinger, P., Borochova, K., Dorofeeva, Y., Henning, R., Kiss, R., Kratzer, B., Mühl, B., Perkmann, T., Trapin, D., Trella, M., Ettel, P., Tulaeva, I., Pickl, W.F. & Valenta, R., 2020. Antibodies in serum of convalescent patients following mild COVID-19 do not always prevent virus receptor binding. Allergy.
  - Hoang, J.A., Celik, A., Lupinek, C., Valenta, R., Duan, L., Dai, R., Brydges, M.G., Dubeau, A., Lepine, C., Wong, S., Alexanian-Farr, M., Magder, A., Subbarao, P., Upton, J.E.M., Schmidthaler, K., Szepfalusi, Z., Ramani, A. & Eiwegger, T., 2020. Modelling the conversion between specific IgE test platforms for nut allergens in children and adolescents. Allergy.
    Link
  - Karsonova, A., Riabova, K., Villazala-Merino, S., Campana, R., Niederberger, V., Eckl-Dorna, J., Froschl, R., Perkmann, T., Zhernov, Y.V., Elisyutina, O.G., Fedenko, E.S., Khaitov, M.R., Fomina, D., Beltiukov, E., van Hage, M., Gronlund, H., Valenta, R., Karaulov, A. & Curin, M., 2020. Highly sensitive ELISA-based assay for quantification of allergen-specific IgE antibody levels. Allergy.
    Link
  - Kratzer, B., Trapin, D., Ettel, P., Kormoczi, U., Rottal, A., Tuppy, F., Feichter, M., Gattinger, P., Borochova, K., Dorofeeva, Y., Tulaeva, I., Weber, M., Grabmeier-Pfistershammer, K., Tauber, P., Gerdov, M., Mühl, B., Perkmann, T., Fae, I., Wenda, S., Fuhrer, H., Henning, R., Valenta, R. & Pickl, W.F., 2020. Immunological imprint of COVID-19 on human peripheral blood leukocyte populations. Allergy.
  - Mittermann, I., Dzoro, S., Gattinger, P., Botha, M., Basera, W., Facey-Thomas, H.E., Gaunt, B., Genuneit, J., Gray, C.L., Hlela, C., Flicker, S., Lunjani, N., Mankahla, A., Ramjith, J., Valenta, R. & Levin, M.Eliad, 2020. Molecular IgE-sensitisation profiles of urban and rural children in South Africa. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
    Link
  - Pazderova, P., Waltl, E.E., Niederberger-Leppin, V., Flicker, S., Valenta, R. & Niespodziana, K., 2020. ELISA-Based Assay for Studying Major and Minor Group Rhinovirus-Receptor Interactions. Vaccines, 8(2).
  - Rodriguez-Dominguez, A., Berings, M., Rohrbach, A., Huang, H.-J., Curin, M., Gevaert, P., Matricardi, P.M., Valenta, R. & Vrtala, S., 2020. Molecular profiling of allergen-specific antibody responses may enhance success of specific immunotherapy. The Journal of allergy and clinical immunology.
  - Smiljkovic, D., Kiss, R., Lupinek, C., Hoermann, G., Greiner, G., Witzeneder, N., Krajnik, G., Trautinger, F., Vrtala, S., Mittermann, I., Kundi, M., Jilma, B., Valenta, R., Sperr, W.R. & Valent, P., 2020. Microarray-based Detection of Allergen-Reactive IgE in Patients with Mastocytosis. The journal of allergy and clinical immunology. In practice.
    Link
  - Tulaeva, I., Cornelius, C., Zieglmayer, R., Schmutz, R., Lemell, P., Weber, M., Focke-Tejkl, M., Karaulov, A., Henning, R., Valenta, R. & Zieglmayer, P., 2020. Quantification, epitope mapping and genotype cross-reactivity of hepatitis B preS-specific antibodies in subjects vaccinated with different dosage regimens of BM32. EBioMedicine, S.102953.
  - Tulaeva, I., Kratzer, B., Campana, R., Curin, M., van Hage, M., Karsonova, A., Riabova, K., Karaulov, A., Khaitov, M., Pickl, W.F. & Valenta, R., 2020. Preventive Allergen-Specific Vaccination Against Allergy: Mission Possible?. Frontiers in immunology, 11, S.1368.
  - Weijler, A.Marianne, Mucha, J., Farkas, A.Michael, Baranyi, U., Pilat, N., Cho, A., Muckenhuber, M., Hopf, S., Wahrmann, M., Linhart, B., Valenta, R. & Wekerle, T., 2020. Methods to Detect MHC-Specific IgE in Mice and Men. Frontiers in immunology, 11, S.586856.
  - Zhao, L., Fu, W., Gao, B., Liu, Y., Wu, S., Chen, Z., Zhang, X., Wang, H., Feng, Y., Wang, X., Wang, H., Lan, T., Liu, M., Wang, X., Sun, Y., Luo, F., Gadermaier, G., Ferreira, F., Versteeg, S.A., Akkerdaas, J.H., Wang, D., Valenta, R., Vrtala, S., Gao, Z. & van Ree, R., 2020. Variation in IgE binding potencies of seven Artemisia species depending on content of major allergens. Clinical and translational allergy, 10(1), S.50.

Forschungsprojekte

Danube-ARC
Danube Allergy Research Cluster - Towards Cure of Allergy
- Projektnummer: K3-T-74/001-2019
- Projektleitung: Rudolf Valenta, Karl Landsteiner Privatuniversität für Gesundheitswissenschaften
- Projektpartner: Karl Landsteiner Privatuniversität für Gesundheitswissenschaften / Klinische Abteilung für Haut- und Geschlechtskrankheiten (UK St. Pölten), Karl Landsteiner Privatuniversität für Gesundheitswissenschaften / Klinische Abteilung für Hals-Nasen-Ohrenkrankheiten (UK Krems), Medizinische Universität Wien, Universität für Bodenkultur, Wien, Universität für Veterinärmedizin Wien, AIT Austrian Institute of Technology
- Projektlaufzeit: 36 Monate ab 01.08.2020

Informationen für

Publikationen

2022

Zeitschriftenartikel

2021

Zeitschriftenartikel

2020

Zeitschriftenartikel

Forschungsprojekte

Danube-ARC

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