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Pharmacology

Research

The Division Pharmacology was established in 2019 by the appointment of Prof. Dagmar Stoiber-Sakaguchi. The research focus of the division is the identification of underlying molecular mechanisms of tumor formation and progression in acute myeloid leukemia (AML), but also in other human cancer types. The identification of potential (drug) targets may be translated into the assessment of new therapy approaches and new tools for prognosis and diagnosis of AML and other tumor diseases. The research is benefitting from the newly established laboratory that allows state-of-the-art molecular biology research (cell- and tissue culture, bioimaging, protein and DNA/RNA analytics, immunology techniques, in vitro and in vivo studies) at the KL and by the team of nationally and internationally well-connected experts.

Basic Research

Comment to Figure: Type I interferon

Current research of the Division Pharmacology focuses on:
 

 

JAK/STAT pathway and its influence in acute myeloid leukemia (AML)

Type I interferon as a mediator between tumors and immune system

STAT3 isoforms – the good and the bad in tumor development

Tumor suppressors and oncogenes in lymphoma

Identification and verification of potential targets for new therapeutic options

 

Applied Research

Events

  1. 15 Dec

    KL Lunchtime Seminar: Towards Natural Killer Cell-Based Immune Therapy in Leukemia

    15. December 2021, 12:00 - 13:00
    Karl Landsteiner University, 3500 Krems/Donau, Wing Y, KL Auditorium
  2. 19 Jan

    KL Lunchtime Seminar: Extramedullary hematopoiesis as part of the innate immune defence against infections

    19. January 2022, 12:00 - 13:00
    Karl Landsteiner University, 3500 Krems/Donau, Wing Y, KL Auditorium
  3. 26 Jan

    KL Lunchtime Seminar: Mechanisms of solute transport through cellular membranes

    26. January 2022, 12:00 - 13:00
    Karl Landsteiner University, 3500 Krems/Donau, Wing Y, KL Auditorium