Heparin binding antimicrobial proteins in human plasma
- Project Number: LSC20-021
- Project Lead: Jens Hartmann, Danube University Krems / Center for Biomedical Technology
- Project Partner: Karl Landsteiner University of Health Sciences / Division Water Quality and Health
- Duration: 36 months starting from 01.03.2022
Background
The aim of this project is to investigate endotoxin-neutralizing mechanisms in human blood. One focus is the influence
of the anticoagulation on the effect of endotoxins and on endotoxin-neutralizing factors in blood. Furthermore, Host
Defense Peptides (HDPs) will be isolated from human whole blood and their influence on the activity of endotoxins will
be investigated. The HDPs will then be characterized with respect to their molar mass.