Psilocybin-assisted psychotherapy in adults with depression – A literature review
Recent Publication
Marie Celine Dorczok MSc, Dr Gloria Mittmann MSc and Dr Verena Steiner-Hofbauer from the Research Centre Transitional Psychiatry have investigated the effectiveness of psilocybin-assisted psychotherapy for depression in a review study. The analysis of seven studies shows that this therapy leads to significant and long-term improvements in symptoms, particularly in difficult-to-treat depression - in some cases up to one year after treatment. Higher doses of psilocybin appear to achieve stronger effects. However, the researchers point out methodological challenges and emphasise the need for standardised study protocols.
Dorczok, M. C., Mittmann, G., Ettl, T., & Steiner-Hofbauer, V. (2025). Psilocybin-assisted psychotherapy in adults with depression – A literature review. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 142, Article 111508. https://doi.org/10.1016/j.pnpbp.2025.111508
Marie Celine Dorczok MSc
Scientific Staff (PreDoc)
Research Centre Transitional Psychiatry
Dr. Gloria Mittmann MSc
Scientific Staff (PostDoc)
Research Centre Transitional Psychiatry
Mag. Dr. Verena Steiner-Hofbauer
Head of
Research Centre Transitional Psychiatry