Microvascular Perfusion MRI Improves Therapy Monitoring and Detects Early Recurrences of Gliomas : A Large-Scale Trial of 2000 Follow-Up Examinations
Recent Publication
In a large-scale study with over 2,000 follow-up examinations, researchers at University Hospital St. Pölten have shown that a special form of perfusion MRI - known as microvascular perfusion (mPerf) - detects recurrences of gliomas significantly earlier than conventional imaging. The method makes tiny changes in the tumour vessels visible, which often occur long before new visible tumour growth. As a result, mPerf was able to detect a relapse many weeks to months earlier in more than 13% of cases. For patients, this means a chance for faster and more individualised therapies.
Stadlbauer, A., Nikolic, K., Marhold, F., Doerfler, A., Kinfe, T. M., Meyer-Bäse, A., Schnell, O., Ökrösi, A., Heinz, G., & Oberndorfer, S. (2025). Microvascular Perfusion MRI Improves Therapy Monitoring and Detects Early Recurrences of Gliomas: A Large-Scale Trial of 2000 Follow-Up Examinations. American Journal of Neuroradiology, 46(12), 2561-2569. https://doi.org/10.3174/ajnr.A8922
Prof. Dr. Andreas Stadlbauer
Institute of Diagnostic and Interventional Radiology (University Hospital St. Pölten)
Dr. Katarina Nikolic
Division of Neurology (University Hospital St. Pölten)
OA Clin. Ass. Prof. PD Dr. Franz Marhold
Division of Neurosurgery (University Hospital St. Pölten)
Dr. Alexandra Ökrösi
Institute of Diagnostic and Interventional Radiology (University Hospital St. Pölten)
Prim. Univ.-Prof. Dr. Gertraud Heinz MBA
Institute of Diagnostic and Interventional Radiology (University Hospital St. Pölten)
Prim. Univ.-Prof. PD Dr. Stefan Oberndorfer FEAN
Division of Neurology (University Hospital St. Pölten)