• Research blog
Monday, 17. November 2025

Impact of weight/BMI on clinical and bleeding events in 26 805 atrial fibrillation patients on edoxaban from the Global ETNA-AF Registry

Recent Publication


 

An international study involving over 26,000 patients has investigated how body weight and BMI influence the risk of stroke, haemorrhage and death in atrial fibrillation. The results show that both very low and very high weight can increase the risk. A U-shaped correlation was particularly striking - i.e. more problems with a very low or very high BMI.

Boriani, G., Kirchhof, P., de Souza, J. A. G., Steffel, J., Koretsune, Y., Chao, T.-F., Weiss, T., Zaremba-Pechmann, L., van Zyl, J., Unverdorben, M., & De Caterina, R. (2025). Impact of weight/BMI on clinical and bleeding events in 26 805 atrial fibrillation patients on edoxaban from the Global ETNA-AF Registry. European Journal of Preventive Cardiology. Advance online publication. https://doi.org/10.1093/eurjpc/zwaf685