• Research blog
Monday, 24. March 2025

High radiation dose in chemoradiotherapy followed by immunotherapy with durvalumab in patients with stage III non-small cell lung cancer does not increase risk for pneumonitis

Recent Publication


 

A new study at Krems University Hospital has investigated whether a higher radiation dose is beneficial in the treatment of non-small cell lung cancer (NSCLC). Patients who were treated with the immunotherapy drug durvalumab following combined radiotherapy and chemotherapy received either a standard radiation dose or a higher dose of 70 Gy. The results show that the higher radiation dose significantly improves the chances of survival without increasing the risk of pneumonia.

Schragel, F., Matousek, M., Resl, C., Kreye, G., Le, N.-S., Errhalt, P., Georg, P., & Hackner, K. (2025). High radiation dose in chemoradiotherapy followed by immunotherapy with durvalumab in patients with stage III non-small cell lung cancer does not increase risk for pneumonitis. Strahlentherapie und Onkologie. Advance online publication. https://doi.org/10.1007/s00066-025-02369-0

Prim. Clin. Ass. Prof. Dr. Peter Errhalt

Division of Pneumology (University Hospital Krems)

Prim. Clin. Assoc. Prof. PD Dr. Petra Georg MBA

Division of Radiotherapy - Radiation Oncology (University Hospital Krems)

OA Clin. Ass. Prof. DDr. Klaus Hackner MSc

Division of Pneumology (University Hospital Krems)