Carbon-Ion Radiotherapy for Head and Neck Mucosal Melanoma: preliminary clinical outcomes and the MedAustron approach for reporting RBE weighted dose with two models
Recent Publication
This study investigated carbon ion beam therapy (CIRT) for aggressive head and neck melanomas that are often resistant to conventional radiotherapy. 14 patients received CIRT treatments, some after incomplete surgery, others only after biopsies. A special dose adjustment was used that took different biological models into account. The results showed that CIRT led to rapid tumor reduction and effectively stopped tumor growth, with very good local control of the tumor. There were few side effects, mostly in the form of inflammation or loss of sense of smell. Although CIRT is a promising treatment option, distant metastasis remains a major challenge for the prognosis of patients.
Nachankar, A., Pelak, M., Schafasand, M., Martino, G., Tubin, S., Hug, E., Carlino, A., Lütgendorf-Caucig, C., Stock, M., & Fossati, P. (Angenommen/Im Druck). Carbon-Ion Radiotherapy for Head and Neck Mucosal Melanoma: preliminary clinical outcomes and the MedAustron approach for reporting RBE weighted dose with two models. International Journal of Particle Therapy, 15, 100738. Artikel 100738. https://doi.org/10.1016/j.ijpt.2025.100738
Univ.-Prof. PD DI Markus Stock PhD
Head of
Department of Medical Physics with an emphasis on Particle Therapy
Univ.-Prof. Dr. Piero Fossati MD
Head of
Department of Radiation Oncology with an emphasis on Particle Therapy