Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract-the B Cell Side
Recent Publication
Allergic diseases such as hay fever and asthma are on the rise worldwide. A new review article, in which Tanja Kalic Kamath PhD from the Division of Dermatology and Venereology (University Hospital St. Pölten) was involved, specifically highlights the role of B cells in the upper airways. The authors show how allergens such as pollen or house dust mites trigger a misdirected immune response via the nasal mucosa and lead to the formation of allergy-causing IgE antibodies. Special attention is paid to local immune processes in the nose, which have been less in the focus of research to date. The work was supported by Danube-ARC funding and emphasises the importance of basic allergy research for future therapies.
Grimsholm, O., Zghaebi, M., Hambrecht, B., Kalic, T., Udoye, C. C., Manz, R., Bohle, B., Sitnik, K. M., Eckl-Dorna, J., & Breiteneder, H. (2026). Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract-the B Cell Side. Allergy: European Journal of Allergy and Clinical Immunology. Advance online publication. https://doi.org/10.1111/all.70229
Tanja Kalic Kamath PhD
Scientific Staff (PostDoc), Scientific Staff (PostDoc)
Scientific Working Group Allergology and Immunology, Division of Dermatology and Venereology (University Hospital St. Pölten)