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NK Cell Symposium Krems

Thu, 04.05.2023 - 09:00 - 17:00
Karl Landsteiner University of Health Sciences, Skylounge

Natural killer (NK) cells are innate lymphocytes able to kill malignant cells. The inborn ability to lyse transformed cells renders NK cells an attractive tool for cancer immunotherapy.

The NK cell symposium brings together research groups who focus on understanding different aspects of NK cell biology.

The groups of Eva König (CCRI), Dagmar Gotthardt (VetMedUni) and Dagmar Stoiber-Sakaguchi (NK cell team led by Agnieszka Witalisz-Siepracka) will present their current research.

The highlight of the symposium is the talk by Dr. Dietmar Herndler Brandstetter, an expert in tumor immunology.


Chairs: Pharmacology  group


                                       9.00-9.15                   Opening

Session I

9.15-9.45                   Theresa Harm - Uncovering NK cell checkpoints in triple negative breast cancer

9.45-10.15                 Agnieszka Witalisz-SieprackaThe role of NK cells in myeloproliferative neoplasms

10.15-10.35               Clio-Melina Sperl - STAT3 in AML escape from NK cell surveillance

                                       10.35-11.00               Coffee break

11.00-11.45               Key note speaker: Dietmar Herndler-Brandstetter – NK cell-targeted cancer therapy in humanized mice

Dietmar Herndler-Brandstetter studied Pharmacy at the University of Innsbruck. After he completed his PhD he continued his research at the University of Birmingham (UK) and further as a postdoctoral fellow in the laboratory of Richard A. Flavell at the University of Yale (USA). Since 2018 he is a group leader (Translational Tumor Immunology) at the Institute for Cancer Research at the Medical University, Vienna. His main interests cover the role of immune system in tumor development and metastasis as well as immune therapies.

                                       12.00-13.00               Lunch

Session II

13.00-13.30               Julia List - The role of Ink4a/Arf in NK cell leukemia

13.30-13.50               Angela  HiesingerThe role of hyperactive STAT5B in natural killer cells

13.50-14.10               Sophie Huszarek - Pharmacological targets to modulate NK cell cytotoxicity

                                      14.10-14.45               Coffee break

Session III

14.45-15.15               Michelle Buri - Revealing unknown evasion mechanisms of leukemic cells from natural killer cells

15.15-15.45               Faith David - Finding novel molecular targets to improve natural killer cell-based therapies to treat leukemia

15.45-16.15               Hayeon Baik - The role of serine/threonine kinase 38 (STK38) in natural killer cells


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