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  • LVLDyn

    • Project Lead: Andreas Reisinger, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: Luxner Engineering ZT GmbH
    • Duration: 6 months starting from 01.04.2022
  • Medi3D Print II


    • Project Number: 10020
    • Project Lead: Gernot Kronreif, ACMIT - Austrian Center for Medical Innovation and Technology
    • Project Partner: Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 36 months starting from 01.01.2022
  • Cortmech-Damage

    Determination of material properties of bone tissue with an adapted two‑layer elasto‑visco‑plastic-damage rheological model

    • Project Lead: Andreas Reisinger, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: Technische Universität Wien / Institute for Lightweight Design and Structural Biomechanics
    • Duration: 5 months starting from 01.09.2021


    Trabecular bone tissue can be properly modeled as an elasto‑visco‑plastic material. However, loading-unloading experiments of individual trabeculae revealed a decrease of the elastic modulus with increasing strain. As such, goal of the current study is to scale the elastic part of a previously developed 2-layer elasto‑visco‑plastic rheological model with a damage variable (from 0-1), which is dependent on plastic strain. This adaptation will enable an improved description of bone tissue material properties. Additionally, new tensile tests will be performed on cortical bone specimens obtained from the shaft of human femurs to compare the usage of the proposed model for cortical and trabecular bone tissue. Additional specimens will be obtained from the femoral neck of healthy and osteoporotic donors to determine if there is a change of material properties of bone tissue with respect to osteoporosis. Previously, it has been shown that there is no significant change of the material properties of individual trabeculae in osteoporosis. Goal of the current study is to investigate if that holds also for cortical bone tissue in the femoral neck. Knowledge of this information is not only essential in computer simulations, which require reliable material input parameters, but also for a better understanding of the effect of osteoporosis on the material itself.


    Mechanical characterization of veneer-wood joints - static tests

    • Project Lead: Andreas Reisinger, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: LUXNER Engineering ZT
    • Duration: 3 months starting from 01.04.2021
  • Failure criterion for bone screws

    A morphology based failure criterion for implanted bone screws

    • Project Number: SC19-014
    • Project Lead: Andreas Reisinger, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 36 months starting from 01.10.2020

    WOODFAT: Mechanical fatigue tests on wood composite panels

    • Project Lead: Andreas Reisinger, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: virtual vehicle Research GmbH
    • Duration: 6 months starting from 01.08.2020
  • ELSA

    Gait-based evaluation of early rehabilitation after ACL reconstruction

    • Project Number: LSC18_018
    • Project Lead: Andrea Zauner-Dungl, Karl Landsteiner University of Health Sciences / Institute of Physical Medicine and Rehabilitation (University Hospital Krems)
    • Project Partner: FH St. Pölten / Institute of Health Sciences, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 45 months starting from 15.01.2020


    A postsurgical treatment after ACL reconstruction is necessary for early return-to-sport as well as to minimize the occurrence of long-term complications. However, the required amount of postsurgical physiotherapeutic supervision remains unclear, as studies concerning less supervision (home-based program) showed sufficient clinical outcomes in home-based groups. Gait plays a major role in rehabilitation process, therefore affordable and simple applicable devices are needed for clinical practice, as 3D gait analysis (gold standard) is expensive. Wearable systems like IMUs (Inertial Measurement Unit) are already used for clinical investigation. Still, there is a lack of appropriate methods and scores for gait assessment, concerning rehabilitation after ACL reconstruction. The aim of the current study is the gait-based assessment of the early rehabilitation progress after ACLre construction.
    For this purpose, a specific ACL rehabilitation score is developed, including multiple aspects of gait as well as clinical parameters. The quality of the score derived by data of a simple, clinically applicable, IMU-based gait analysis device (G-Walk) is evaluated in comparison to a standard 3D gait analysis system. Based on the developed score, the outcome of two different ACL rehabilitation programs (home-based versus standardized) will be determined. Therefore, a clinical study is conducted. Two groups of patients with different postsurgical treatment after ACL reconstruction will be formed. Gait assessments will be carried out 6-7 weeks, 9-10 weeks and 12-13 weeks postsurgical using a simple IMU-based gait analysis system (G-Walk) as well as standard 3D gait analysis system for validation purpose. Pre-existing gait data of healthy people will serve as a control. A new ACL habilitation score will be developed, including clinical parameters (e.g. range of motion, IKDC, Lysholm), standard gait parameters (regarding kinematics, kinetics and spatiotemporal characteristics) as well as more sophisticated gait parameters like symmetry, variability, complexity or local stability. Statistical analysis will be performed to determine the influence of the rehabilitation programs and the adequacy of the score determined from IMU data compared to 3D gait analysis data. The results of the proposed study will not only give information about the impact of physiotherapeutic supervision on the early normalization of gait and if home-based programs can confidently be recommended for specific patients. It will also provide a clinically applicable method for gait assessment which can be integrated in the routinely follow-up procedure after ACL reconstruction and used to answer related scientific questions. Furthermore, the proposed method can lay the basis for the development of similar scores in different fields of rehabilitation or therapy assessment.

  • Measurement of mechanical strains

    Measurement of mechanical strains on the surface of biological tissues

    • Project Number: SC18-006
    • Project Lead: Dieter Pahr, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 26 months starting from 01.07.2019


    Bone is a fascinating, living, and smart load-bearing tissue. It supports the body, facilitates locomotion and acts as protector to inner organs. Understanding of bone mechanical properties helps in developing treatments and clinical applications suitable for more complex and personalized solutions.
    In general, biological tissues are inhomogeneous and anisotropic. To understand mechanical behaviour of biological tissues, a complete description of this behaviour over the whole geometry and shape of the sample is necessary. Bone and soft tissues mechanical properties have been widely investigated with different approaches, such as in vitro experiments and numerical models. Experimentally, strain gauges (SGs) are considered as gold-standard for strain measurements on the bone surface due to their high accuracy. However, measurements with the SGs allow only for discrete points to be evaluated and do not provide full-field strain distribution on the surface of the sample. In addition, SGs require detailed surface preparation. A poor preparation can result in extremely inaccurate results. Transducers and extensometers have been used as well to measure the global strain in bone. All the previous three strain measurement techniques induce perturbation in the results due to their contribution to the load-bearing capacity, lead into a systematic underestimate of the actual strain distribution.
    During the last years, optical measurement techniques based on digital image correlation (DIC) paired with computational power allowed contactless measurement of whole surfaces. Thus, they overcome the limitation of contacting the surface and availability of single measurement points.
    DIC depend on tracking the displacement of recognized features (speckles) on the sample surface. DIC tracks the displacement between deformed and un-deformed digital images of the surface. Based on the digital images, a full-field displacement map is calculated from which a full-field strain map is derived. The accuracy of DIC depends on the quality of the speckles, measurement conditions (light and speckle size and distribution), as well as various software (facet and grid size) and hardware parameters (optics and camera resolution), which must be optimized. Despite the versatile advantages of DIC approach in obtaining full-field strain measurements on the surface of interest, DIC has not been fully exploited yet for measurements on biological samples, and in particular, on bone.
    The aims of this study are: (i) extensively investigate the accuracy and precision of the DIC method based on standardized metallic and polymeric samples under zero-load by evaluating the speckle pattern size and distribution, (ii) validation of the accuracy and precision of DIC measuring system against a precise extensometer; (iii) evaluate 3D full-field strain distribution on the surface of biological tissue like bone and tendon samples; (iv) provide practical guidelines on how to harness the benefits of DIC application to measure strain fields on biological hard and soft tissues.

  • OsteoScrew

    A morphology based failure criterion for implanted bone screws

    • Project Number: LSC17_004
    • Project Lead: Andreas Reisinger, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: AIT Austrian Institute of Technology / Center for Health & Bioresources
    • Duration: 48 months starting from 01.06.2019


    In modern orthopedic surgery, the complication rate due to bone screw breakout and loosening during the convalescence period is still substantial. The surgeon's decision, whether an implanted screw will bear the occurring loads or not, is mainly based on the personal- or clinical experiences. This research project aims to improve the current situation by developing a computer based method which is able to estimate the failure risk of a bone screw prior its implantation. In particular it is hypothesized that the (multi-axial) failure load of an individual bone screw can be predicted by local morphological parameters at its implantation position. This morphological information is based on computer tomography (CT) scans of the fractured bone. In a mid-term perspective, this morphologically-based screw failure criterion could find its way into pre-operative computer planning tools to be used by surgeons for determining the optimal implant position and screw number in advance. Such a clinical tool could lead to more successful surgeries, less costly complications, and higher quality of life for the patient. For developing this screw failure criterion, the idea of bone biopsies studies is followed. A high number of bone samples with screws will be prepared in the laboratory and scanned with a micro-CT system in order measure the local bone morphology. Biomechanical testing in multiple directions will provide data about the mechanical competence of the bone screws including the relevant failure mechanisms. The obtained screws’ failure loads will be related to the samples’ histomorphometric parameters and expressed in a failure surface. With that failure surface, the failure risk of a bone screw can be predicted based on local bone morphology and a loading state prior implantation. In this study standard titanium screws as well as screws made from biodegradable magnesium will be evaluated. This magnesium alloy degrades naturally in the environment of a living body and could make the extraction of implants obsolete. To gain deeper knowledge about that promising material, the failure loads of magnesium screws at multiple degradation states will be compared with standard titanium screws.

  • FAM-3D

    Functional anatomical 3D-models

    • Project Number: K3-F-807/002-2018
    • Project Lead: Nikolaus Dellantoni, ACMIT - Austrian Center for Medical Innovation and Technology
    • Project Partner: Karl Landsteiner University of Health Sciences / Division of Biomechanics, Niederoesterreichische Landesgesundheitsagentur (NOE LGA) / X-ray Institute for Diagnostics, Interventional Radiology and Nuclear Medicine
    • Duration: 45 months starting from 01.04.2019
  • Colon-Plug


    • Project Number: 874254
    • Project Lead: Dieter Pahr, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: Teaching ordination / Prim. Univ.-Prof. Dr. Georg Bischof
    • Duration: 12 months starting from 01.03.2019
  • Reproducing biological tissues

    Reproducing biological tissues in terms of their mechanical properties by means of 3D printing

    • Project Number: SC17-016
    • Project Lead: Dieter Pahr, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 34 months starting from 01.12.2018


    3D printing, also known as additive manufacturing (AM) or rapid prototyping, has become a highly versatile tool with a broad range of applications, such as manufacturing, art, design, and medicine. In the field of biomedical engineering AM has not only gained wide popularity in tissue engineering for printing scaffolds and in biomechanics for patient-specific prostheses, but it has also been proposed as an instrument for fabricating realistic 3D models. For example, individual modelling of patient-specific conditions via AM poses an excellent opportunity for surgeons to practice procedures beforehand. Studies have shown that in doing so operation time is reduced and the physician's confidence is increased, resulting in shorter times of radiation exposure and lower costs. Although 3D modelling approaches for pre-surgical planning have been reported previously, a closer look, concerning the mechanical properties of the printed materials, is still required. Currently, these models lack accurate representation of the tissue biomechanics. This demands a procedure for fine-tuning the mechanical properties of the 3D printed materials to closely match the in vivo conditions. In this project, 3D printing is applied to the task of producing materials that closely imitate biological tissues, and organ-like structures, in terms of their mechanical properties. The printed tissues can be patient-specific for pre-surgical planning, as well as standardized for applications in research dealing with advancing novel operating techniques, implant technology, and other medical devices. One of the incentives is to thereby limit the demand of donor organs and reduce variability of the organs used in research. Due to the fact that the capabilities of 3D printing are currently rapidly increasing, this research can also be seen as the groundwork for even more applications concerning printed organs that might be possible with future technology. The key objectives of this project are:
    the establishment of a testing protocol for acquiring characteristic biomechanical parameters of different tissues, the development of software tools for attaining these parameters in 3D printed structures (based on suitable material combinations and spatial distribution thereof, plus post-processing procedures), the printing of these tissue replicas alongside the validation of their mechanical properties via comparison with the actual tissue characteristics. All instructions for manufacturing these models are to be contained in a so-called “toolbox”.

  • Digitisation as a chance for restoration and visualisation

    Digitisation as a chance for restoration and visualisation – A pilot study on the 30,000 year old double burial of newborns from Krems-Wachtberg

    • Project Number: FTI17-010
    • Project Lead: Dieter Pahr, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: Museum of Natural History Vienna / Department of Anthropology, Danube University Krems / Collection Studies and Management, Austrian Academy of Science / Institute for Oriental and European Archaeology
    • Duration: 47 months starting from 01.11.2018


    The discovery of the more than 30,000 years old ritual double burial of two neonates at the Krems-Wachtberg site in 2005 has evoked much attention not only by the media and the general public, but also from the international scientific community as findings of sub adults of ancient humans are, on a global scale, extremely rare occasions. After the discovery and exposure the ritual burial was carefully recovered as a block, and the fragile specimens were stored to keep its original excellent condition. In 2015 the recovered block was excavated, documenting each single step with state-of-the art methods.
    Digitisation is now aimed for to enable analyses, restoration and also visualisation. Currently, the only non-destructive way to make a digital copy and visualize the remains is high-resolution micro-computed tomography imaging. It allows 3D reconstruction of the surface as well as the inner micro-structure - making it possible to “uncover the invisible”. Such a device has been installed at the division for Biomechanics of KL University as part of the Core Facility at Campus Krems. This will overcome the current restrictions of analysis and allows a digitisation of the findings for future analysis.
    Together with the available light scanning data from the excavation the whole assembly can be reconstructed. Apart from 3-dimensional reconstruction it will be possible to restorate the chaîne operatoire of activities which were part of this burial process, as well as the post-sedimentary formation processes (4D = modelling the development through time).
    In addition to the reconstruction of the burial, up-to-date documentation and archiving of the data is of utmost importance to lay a basis for further research. Thus, one of the main objectives of this pilot project is to set up a catalogue of criteria for a long term, open-source data repository which provides access to all the data regarding the excavation and findings for larger groups of scientists beyond disciplinary borders.
    Digitisation of the Krems-Wachtberg double burial is challenging in all respects and requires a variety of experts to deal with the many aspects that are inherent in such a spectacular discovery. For the first time, it is possible to investigate this outstanding find from Krems-Wachtberg under the leadership of Lower Austrian research institutions. As one of its main targets, the proposed project will contribute to a further professionalization in Collection Management and Museology – one of the areas of Lower Austrian FTI strategy – and it will significantly improve the visibility of cultural heritage in Lower Austria by latest technical developments that allow for scientific exploitation on an international level.

  • HIPStar

    Obesity-specific joint center estimation in gait analysis

    • Project Number: P 30923-B30
    • Project Lead: Brian Horsak, FH St. Pölten / Institute of Health Sciences
    • Project Partner: Karl Landsteiner University of Health Sciences / Division of Biomechanics, Medical University of Vienna / Department of Pediatrics and Adolescent Medicine, Orthopaedic Hospital Vienna-Speising
    • Duration: 36 months starting from 01.10.2018


    Gait analysis aims at gathering quantitative information about the mechanics of the musculo-skeletal system during locomotion. Typically, in gait analysis, variables such as kinematics, joint moments, and powers are determined. This information is used to evaluate pathological gait patterns. Errors in locating the three-dimensional (3D) position of the hip joint center (HJC) can strongly affect the calculation of 3D gait analysis variables. This consequentially leads to incorrect interpretations. The problem of inaccuracy in HJC location increases significantly in patients where bony landmarks are difficult to identify, such as in overweight or obese populations. Nevertheless, gait analysis remains as the state of the art method for clinicians and for researchers. Often medical imaging-based methods are recommended to identify the 3D HJC localization. However, some of those methods expose patients to radiation or are expensive and time-consuming. Therefore, non-invasive predictive methods, based on experimental data, or functional models were introduced in recent years to estimate the position of the HJC. Researcher has attempted to evaluate which of these methods best determine the HJC most accurately in various populations. Among those, only a few studies recruited children or clinically diagnosed patients. Surprisingly, there is no study, which recruited overweight or obese children and adolescents. However, all currently non-invasive available methods are strongly affected by the amount of subcutaneous fat present (wobbling mass), which can introduce great inaccuracies. Therefore, a study to identify how well existing HJC estimation methods work for this very specific population is strongly recommended. In addition, new methods such as 3D free-hand ultrasound techniques (3DUS) may bear great potential for accurate and non-invasive estimation techniques. These methods, are still experimental and have not yet been tested in overweight populations.
    The primary aim of this study is to evaluate the accuracy of current non-invasive HJC estimation methods for clinical 3D gait analysis to magnetic resonance imaging (MRI) in a population of overweight or obese children and adolescents. Based on the results obtained in this study, we will (i) provide recommendations, for which methods serve best to estimate the HJC position; (ii) develop soft tissue compensation algorithms and strategies that allow for a more accurate estimation of the HJC; (iii) in addition, we will evaluate the use of 3DUS as a promising alternative in HJC estimation.

  • BEST MgAlloy

    Biocompatible elements - simulations and tests for Mg alloys

    • Project Number: KF3-F-639/004-2017
    • Project Lead: Jelena Horky, AIT Austrian Institute of Technology / Center for Health & Bioresources
    • Project Partner: Aerospace & Advanced Composites GmbH, FH Wiener Neustadt, AC2T research GmbH, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 42 months starting from 01.04.2018


    Biodegradable magnesium-based implants are increasingly coming into focus for temporary use in medical applications, such as plates, nails, pins or screws for osteosynthesis of broken bones. The great advantage of this is the elimination of a second operation for explanting any permanent metallic fixations.

  • Medi3D Print

    3D print of biological materials

    • Project Lead: Gernot Kronreif, ACMIT - Austrian Center for Medical Innovation and Technology
    • Project Partner: Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 39 months starting from 01.01.2018


    3D printing is entering medicine and can help in many ways. In addition to accurately fitting implants and orthoses, 3D printing can be used in surgical preparation to gain a better understanding of the planned surgery. Increasingly, the printing of organs is becoming more important. In this research project materials are to be printed with the help of the Polyjet process which come as close as possible to real biological tissues from the haptic but also with regard to the biomechanical behavior. The printing technology developed in this way enables the production of patient-specific organ models based on CT and MRI data, which can be used for preoperative planning prior to complicated procedures. Furthermore, for the further development of surgical techniques and implants mechanically equivalent organs or specimens can be produced, which make dispensing with the use of body donations for these concerns. The printed organs are standardizable and have no undesirable variability, as is the case with body donation.

  • Endobone

    Developmental tissue engineering model of endochondral ossification for bone regeneration

    • Project Number: LSC16_024
    • Project Lead: Stefan Nehrer, Danube University Krems / Department of Regenerative Medicine
    • Project Partner: Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 48 months starting from 01.01.2018


    Bone engraftment techniques to treat large bone defects involve implantation of allogenic bone grafts as a replacement tissue but are constrained on poor integration and functional anastomosis for ingrowth of vasculature from the host tissue. In proportionate many unresolved factors are to be addressed in advancing the clinical outcome for treating fracture non-unions, osteonecrosis, osteoporosis. Tissue engineering strategies hold promise in promoting bone regeneration. Nevertheless, the common approach in bone tissue engineering is by stimulating the osteogenesis route for regenerating bone which still remains an ineffective approach. Mimicking the natural process of bone formation through a developmental mechanism for formation of long bones called endochondral ossification has been envisioned from the commencement of research in the field of bone tissue engineering. In the current proposal, we propose a strategy for bone regeneration with naturally derived biomaterials incorporating extracellular matrix derived from cartilage (CD-ECM) as a template. We hypothesize that bone regeneration through a cartilaginous intermediate template onto solid biomaterials will produce a neotissue that mimics the native bone in its structure and functionality. To test this hypothesis we will compare bone regeneration from the proposed model to the gold-standard bone allografts used in clinics. CD-ECM incorporated biomaterials embedding hypertrophic chondrocytes are evaluated for their mineralized matrix formation in vitro with biochemical analysis and histological evaluation. Further, by non-destructive analysis micro-computed tomography (µCT) monitoring generated 3D segmented images and biomechanical testing of the scaffolds are evaluated together with computational finite element modelling simulations to determine the stiffness, strength of the engineered bone. The CD-ECM incorporated biomaterials are then implanted with or without hypertrophic chondrocytes ectopically in a mouse model for de novo mineralized matrix formation. The bone formation is further assessed by biochemical, µCT, biomechanical, computational modelling. This interdisciplinary approach would aid in a developmental engineering process instructing bioresponsive scaffolds to recapitulate native bone repair mechanisms.

  • Novel biomechanical test setup

    Development of a novel biomechanical test setup together with bone strength simulation models to improve the diagnoses and treatment of osteoporosis

    • Project Number: SC16_009
    • Project Lead: Dieter Pahr, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 37 months starting from 01.10.2017


    Osteoporosis (OP) is a silent bone disease resulting in loss of bone density, decreased bone strength and ultimately fracture. It is underrated, underdiagnosed and undertreated. Every third women and every fifth men over 50 are concerned. OP is responsible for more than 4 million fractures annually in the EU, with hip fracture as the most common type. This translates into more than €40 billions of health care costs, out of which less than 5% is spent on prevention. Beside diabetes, cardiovascular diseases, and cancer it’s one of the important health care challenges in the next decades. Especially in Lower Austria this puts an estimated €200 million of annual burden on the healthcare system only. The early diagnostics of OP is vital for fracture prevention. This in return increases the life quality of the patient, and decreases the healthcare and social costs. Bone density is used as predictor of osteoporotic fracture risk. It is measured with DEXA and diagnosed with a derived T-score. However, recent studies showed the inaccuracy and insufficiency of such densitometry measures. For example, more than 50% of OP fractures occur in the patients who are considered as “low risk” by this method, and 15% of patients are falsely treated for being at "high risk". An improvement of this situation needs (a) better screening techniques, (b) more screening, and (c) improved diagnosis scores. The goal of this project is to improve osteoporosis diagnostic tools. Bone fracture happens because of overloading and/or reduced resistance against loading due to bone loss. Finite element analysis (FEA) simulation is a non-invasive numerical method which is able to estimate individual bone strength in-vivo based on DEXA or Quantitative Computed Tomography (QCT) images. Geometrical, structural, and material properties are computed from images and combined with typical physiological loading conditions including the magnitude, direction, and frequency of the loading. The accuracy of the model is inherited from a good knowledge of all these parameters. FEA -based bone strength has the potential to effectively improve diagnosis, assessment, and monitoring of osteoporosis. But despite the significant progress made in the last decade, these predictions still need considerable improvements through enhancements in imaging, mechanical testing, and simulation techniques to justify their clinical use.

  • M3dRES

    Additive Manufacturing for Medical Research

    • Project Number: FFG858060
    • Project Lead: Francesco Moscato, Medical University of Vienna / Center for Medical Physics and Biomedical Engineering
    • Project Partner: ACMIT - Austrian Center for Medical Innovation and Technology, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Duration: 60 months starting from 01.05.2017


    The M3dRES project aims at establishing a unique infrastructure devoted to 3d-printing for medical research in a strongly interdisciplinary environment.
    M3dRES provides essential tools for the personalized patient treatment, for the enhancement of medical imaging, for the acceleration of tissue engineering and regenerative medicine, and for the modernization of current medical education.

  • OsteoSim

    Computer simulation models for the early detection of osteoporosis

    • Project Number: FFG850746
    • Project Lead: Dieter Pahr, Karl Landsteiner University of Health Sciences / Division of Biomechanics
    • Project Partner: Danube University Krems / Department of Regenerative Medicine, Braincon GmbH&CoKG, Technische Universität Wien / Institute for Lightweight Design and Structural Biomechanics
    • Duration: 36 months starting from 01.12.2015


    Osteoporosis is a common age disease of the bone. The cause of osteoporosis is usually a hormonal change. Older women are predominantly affected, but men are also increasingly suffering from this disease. The widespread of osteoporosis is gradually becoming a health economic problem. Osteoporosis gradually reduces bone density. As a result, the entire skeleton is weakened biomechanically and it is more likely to suffer from bone fractures. In clinical practice, the diagnosis of osteoporosis or, in general, the estimation of a fracture risk on the basis of bone density measurement (BMD measurement) is carried out. According to WHO, a T <-2.5 standard deviation is the critical threshold for the diagnosis of osteoporosis. Unfortunately, results of studies (eg, Rotterdam study3) show that in a group with non-vertebral fractures, only 44 percent of women and 21 percent of men had a value below -2.5. The final goal is to combine both medical reports from osteoporosis and osteoarthrosis together with new, validated assessment models, which gives better results than the T-score. As a secondary goal, relationships and possible interactions of both diseases are shown. This is to be achieved by four research tasks: new models of osteoporosis, standardization of radiographs, combined findings - correlations osteoporosis and osteoarthrosis, validation of new osteoporosis assessment models.


  1. 05 Jun

    Queer Movie Night

    05. June 2023, 18:00 - 22:00
    Kino im Kesselhaus
  2. 21 Jun

    Lunchtime Seminar Series: TBA

    21. June 2023, 12:00 - 13:00
    Karl Landsteiner Privatuniversität, TBA
  3. 04 Jul

    The Mirage of Biosocial Complexity: Critique and Collaboration Around the Tools of Epigenetics

    04. July 2023, 17:00
    Vienna BioCenter, IMBA lecture hall, Dr.-Bohr-Gasse 3, 1030 Vienna. (It will be possible to participate online.)